Xifaxan Patient Assistance Program - Apply Now

Simplefill works to help Americans who can’t afford the medications they need to manage chronic medical conditions and maintain their health. Learn about our Xifaxan patient assistance program, and apply today.

What Is Xifaxan?

Xifaxan is used to treat irritable bowel syndrome with diarrhea (IBS-D) as well as the diarrhea often referred to as “traveler’s diarrhea,” which is caused by E. coli bacteria. It is important to note that Xifaxan is not intended to treat diarrhea caused by viral infections like colds or flu.

Xifaxan is a fairly expensive antibiotic that is effective at stopping the growth of the bacteria that causes gastric infections and the associated abdominal pain and diarrhea. A two-week treatment period can provide symptomatic relief of IBS-D for an average of 10 weeks, and possibly up to 24 weeks. As with all antibiotics, it is important to take this medication exactly as prescribed, completing the full course of treatment without interruption.

Xifaxan is also prescribed to treat hepatic encephalopathy, a brain disorder associated with advanced liver disease.

How Does Xifaxan Work?

Xifaxan (rifaximin) is based on an older antibiotic, rifamycin. In addition to being an effective antibiotic, it has anti-inflammatory properties. As a non-absorbable antibiotic, Xifaxin has a low bioavailability due to poor oral absorption. Consequently, it remains in the GI tract and acts directly on local bacterial infections. Unlike many antibiotics, Xifaxan retains its effectiveness in patients that have undergone multiple courses of treatment over time, which is common with irritable bowel syndrome.

Xifaxan is also prescribed preventively for people with advanced liver disease to decrease the risk of hepatic encephalopathy, or HE. HE impairs brain function due to a buildup of ammonia in people whose livers can no longer filter poisons from the blood. Xifaxan reduces that buildup, making HE less likely.

How to Get Xifaxan Prescription Assistance

To get the help you need paying for your Xifaxan prescription, apply to Simplefill online or by phone at 1(877)386-0206. Within 24 hours, you’ll get a call from a Simplefill advocate who will collect the information we need to identify the Xifaxan prescription assistance programs you qualify for.

We’ll do the heavy lifting and submit applications to those programs on your behalf. Once we hear that you’ve been approved, we’ll go ahead and get you enrolled without delay so you can start getting help paying for your Xifaxan prescription as soon as possible.

That’s not the end of our assistance, though. We’ll make sure your Xifaxan prescription is renewed when needed, and we can connect you with assistance programs that can help you pay for any new medications prescribed to you as well.